A Study of VRT106 for Injection in Patients With Recurrent/Progressive Glioblastoma

This study is testing a new treatment called VRT106 for people with glioblastoma (a fast-growing and aggressive type of brain tumor) that has come back or continued to grow after previous treatment. VRT106 is an experimental drug being investigated to see if it can slow or stop tumor growth. **You may be eligible if...** - You are 18 to 70 years old - You have been diagnosed with recurrent or progressing glioblastoma - You are in reasonably good physical condition (Karnofsky score of 60 or higher) - You have a life expectancy of at least 3 months - Your organs are functioning adequately **You may NOT be eligible if...** - Your glioblastoma has spread outside the brain - You have previously received oncolytic virus therapy or gene therapy for cancer - You have taken another experimental drug within the past 4 weeks - You are allergic to any ingredient in VRT106 - You cannot have an MRI scan of your head - You are breastfeeding Talk to your doctor to see if this trial is right for you.