Food Effect, Efficacy and Safety of MKP10241 in Healthy and Obese Adult Participants, With and Without Diabetes

This study is testing a new investigational drug called MKP10241 to evaluate how food affects its absorption, and whether it is safe and effective for healthy people, people with obesity, and people with type 2 diabetes. The study takes place in a clinical research unit where participants stay for observation. **You may be eligible if...** - You are aged 18–60 - (Part 1): You are healthy with a normal BMI (18–30) and normal fasting blood sugar - (Part 2): You are healthy with obesity (BMI ≥32) and normal fasting blood sugar - (Part 3): You have type 2 diabetes managed by diet alone or stable metformin - You are a non-smoker or very light social smoker - You are willing to stay at the research unit and follow all restrictions **You may NOT be eligible if...** - You have liver, kidney, or significant blood abnormalities - You have a history of non-fever-related seizures - You have had major surgery in the past 60 months or plan surgery during the study - You have any history of malignant cancer (with minor exceptions) - You test positive for HIV, hepatitis B, or hepatitis C - You are pregnant or planning to become pregnant - You have had significant weight changes (±10%) in the past 3 months - You are currently taking medications other than paracetamol Talk to your doctor to see if this trial is right for you.