Puberty Clinical Trials

10 recruiting

Puberty Trials at a Glance

23 actively recruiting trials for puberty are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Charlottesville, Shanghai, and Research Triangle Park. Lead sponsors running puberty studies include University of Virginia, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and Children's Hospital of Fudan University.

Browse puberty trials by phase

Treatments under study

About Puberty Clinical Trials

Looking for clinical trials for Puberty? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Puberty trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Puberty clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

Disorders of Sex Development (DSD)Pediatric and Adolescent Cancers of the Genital TractReproductive Endocrine Conditions in Puberty+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)11,000 enrolled1 locationNCT04717349
Recruiting

Investigating the Impact of Obesity on Pubertal Development in Girls

ObesityNormal PhysiologyPuberty
National Institute of Environmental Health Sciences (NIEHS)150 enrolled1 locationNCT02583646
Recruiting

Natural History Study of Patients With Excess Androgen

Congenital Adrenal Hyperplasia (CAH)Familial Male-Limited Precocious Puberty (FMPP)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)3,000 enrolled2 locationsNCT00250159
Recruiting
Not Applicable

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

Insulin ResistancePhysical ActivityPCOS (Polycystic Ovary Syndrome)+1 more
Massachusetts General Hospital40 enrolled1 locationNCT07102797
Recruiting
Not Applicable

Early Breast Growth in Girls Aged 6 to 8 Years in the Current Environmental Context

BreastEnvironmental ExposurePuberty, Precocious
Lille Catholic University62 enrolled2 locationsNCT06083415
Recruiting
Phase 3

A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty

TreatmentPrecocious PubertyAcupuncture+1 more
Children's Hospital of Fudan University170 enrolled2 locationsNCT06510764
Recruiting

Idiopathic Central Precocious Puberty and Associated Neurodevelopmental Syndromes and Pathologies: Evaluation of Frequency and Comparison of Diagnostic and Developmental Characteristics

Central Precocious Puberty (CPP)
IRCCS Azienda Ospedaliero-Universitaria di Bologna300 enrolled1 locationNCT06720844
Recruiting

IDMet (RaDiCo Cohort) (RaDiCo-IDMet)

Beckwith-Wiedemann SyndromePrader-Willi SyndromePseudohypoparathyroidism+6 more
Institut National de la Santé Et de la Recherche Médicale, France2,000 enrolled20 locationsNCT05945576
Recruiting
Not Applicable

Growth Evaluation, Health Promotion, and Clinical Management in Children and Adolescents With Thalassemia

Thalassemia MajorThalassemia IntermediaGrowth Delay+1 more
Institute of Hematology & Blood Diseases Hospital, China369 enrolled1 locationNCT06931912
Recruiting

First Observatory of Precocious Puberty.

Puberty, Precocious
Hospices Civils de Lyon3,360 enrolled25 locationsNCT06263868
Recruiting

Observation of Environment and Reproductive-Endocrine Effects

HypogonadismPrecocious PubertyAmenorrhea+2 more
National Institute of Environmental Health Sciences (NIEHS)300 enrolled1 locationNCT06280807
Recruiting
Early Phase 1

Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

PubertyHyperandrogenism
University of Virginia36 enrolled1 locationNCT00929006
Recruiting
Early Phase 1

Hyperandrogenemia and Altered Day-night LH Pulse Patterns

Polycystic Ovary SyndromePubertyHyperandrogenism
University of Virginia32 enrolled1 locationNCT03068910
Recruiting
Early Phase 1

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

Polycystic Ovary SyndromePubertyHyperandrogenism
University of Virginia32 enrolled1 locationNCT04723862
Recruiting

The Molecular Basis of Inherited Reproductive Disorders

Kallmann SyndromeHypogonadotropic HypogonadismReproductive Disorder+1 more
Stephanie B. Seminara, MD600 enrolled1 locationNCT05971836
Recruiting
Not Applicable

Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls

PsychopathologyPubertyRejection Sensitivity
Washington University School of Medicine250 enrolled1 locationNCT06777823
Recruiting
Phase 4

Indicators and Evaluation of Efficacy of Yin-nourishing and Fire-reducing Chinese Medicine for Girls With Rapid Progression of Early Puberty

Puberty Changes
Children's Hospital of Fudan University80 enrolled1 locationNCT06820931
Recruiting

Negative Emotionality and Epigenetics During Puberty

StressHealthyPuberty
International Research Training Group 2804100 enrolled1 locationNCT06690866
Recruiting

Ovarian Morphology in Girls

PubertyAmenorrheaOligomenorrhea
Cornell University60 enrolled3 locationsNCT04424576
Recruiting

Identifying New Genetic Causes to Development Disorders

Growth DisordersDisorders of Sex DevelopmentPuberty Disorders
Fondation Ophtalmologique Adolphe de Rothschild1,100 enrolled1 locationNCT03283852