RecruitingNCT07106294

Hyperspectral Imaging for Prediction of Preeclampsia

Systematic Evaluation of Hyperspectral Analysis as a Predictive Marker of Preeclampsia


Sponsor

Heidelberg University

Enrollment

1,430 participants

Start Date

Aug 21, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Preeclampsia is a hypertensive pregnancy disorder that can quickly lead to serious, potentially life-threatening outcomes for both the mother and the fetus. Typical features of preeclampsia are by endothelial and microvascular dysfunctionsNotably, such impairments in endothelial function may precede preeclampsia diagnosis and canpersist for years postpartum. In clinical practice, however, no predictive methods have yet been established that specifically reflect endothelial dysfunction in the context of preeclampsia. Hyperspectral imaging represents a new and non-invasive imaging modality that allows contact-free visualization of peripheral microcirculatory dynamics and tissue perfusion. Despite its growing use in other medical fields, this technology has not yet been systematically studied to determine its predictive potential in preeclampsia. The HIPPA project (Systematic Evaluation of Hyperspectral Analysis for Prediction of Preeclampsia) is a prospective observational study to evaluate the applicability of hyperspectral imaging as a new tool for prediction of preeclampsia.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a special type of light-based imaging called hyperspectral imaging can predict which pregnant women may develop preeclampsia — a serious condition involving high blood pressure during pregnancy. The imaging is non-invasive and done during a routine ultrasound visit. **You may be eligible if:** - You are pregnant with a single baby - You are 18 years or older - You are scheduled for a routine first or second trimester ultrasound - You are able to give informed consent **You may NOT be eligible if:** - You do not consent to participate - There is a language barrier that prevents participation - Your baby has been diagnosed with serious chromosomal or genetic abnormalities - You smoked in the 2 hours before the measurement - You have already been diagnosed with preeclampsia Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Heidelberg University Hospital, Department of Gynecology and Obstetrics

Heidelberg, Germany

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NCT07106294


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