RecruitingNCT07130565

Pan-Amyloid PET/CT in Various Amyloid-Related Disease


Sponsor

Tianjin Medical University

Enrollment

500 participants

Start Date

Nov 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

To evaluate the potential usefulness of 18F-92/AV45/TPZA/FT8, 11C-PIB positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Pan-Amyloid-related disease patients.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a newer type of PET/CT scan — called a Pan-Amyloid scan — that can detect abnormal protein buildup (amyloid) in different tissues, especially the heart, in people with suspected or confirmed amyloid-related disease. **You may be eligible if...** - You are 18 or older - You have suspected or confirmed cardiac amyloidosis (amyloid buildup in the heart), supported by MRI, CT, blood tests, or a biopsy - You are already scheduled for a Pan-Amyloid PET/CT scan - You are able to give written consent (or have a parent/legal guardian who can) **You may NOT be eligible if...** - You do not have an amyloid-related condition (the lesion has a different cause) - You are pregnant - You are unwilling or unable to provide written consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TEST18F-92/AV45/TPZA/FT8, 11CPIB

Each subject receive a single intravenous injection of 18F-92/AV45/TPZA/FT8, 11C-PIB and undergo PET/CT or MRI imaging within the specificed time.


Locations(2)

The First Affiliated Hospital of University of Science and Technology of China

Hefei, Anhui, China

Tianjin Medical University General Hospital

Tianjin, Tianjin Municipality, China

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NCT07130565


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