RecruitingPhase 4NCT07135453

Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

Novel Serotype Alert: Investigate New Pneumococcal Conjugate Vaccines for Inducing Cross-protection Against Newly Discovered Serotype 33E and Putative Novel Serogroup 33 Serotypes


Sponsor

University of Alabama at Birmingham

Enrollment

70 participants

Start Date

May 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to learn whether different types of vaccines to prevent bacterial infections are able to effectively create antibodies that defend against certain types of bacteria. We will give two different types of vaccine and evaluate the effectiveness of antibodies produced by each vaccine in killing bacteria.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Healthy adult

Exclusion Criteria2

  • No prior history of pneumococcal vaccination
  • No immunosuppressing medications or chronic diseases that affect immune function

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Interventions

BIOLOGICALPneumococcal Vaccine

PCV


Locations(1)

University of Alabama at Birmingham

Birmingham, Alabama, United States

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NCT07135453


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