RecruitingNot ApplicableNCT07140848

CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes

A Novel Continuous Glucose Monitoring Enhanced DPP Intervention to Prevent Type 2 Diabetes in Adults With Prediabetes

Sponsor

State University of New York at Buffalo

Enrollment

214 participants

Start Date

Apr 13, 2026

Study Type

INTERVENTIONAL

Conditions

Prediabetes

Summary

Prediabetes affects over one-third of adults in the United States, placing them at a higher risk for developing type 2 diabetes and heart disease, which can lead to serious health complications and increased medical costs. Although a program called the Diabetes Prevention Program (DPP) has been shown to lower the risk of diabetes through healthy lifestyle changes, many people find it difficult to stick with these changes over the long term. This study seeks to find out if combining DPP coaching with continuous glucose monitoring (CGM) technology can help people stay on track with their health goals.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

adults aged 18 years or older,
diagnosis of prediabetes, as defined by current clinical guidelines (HbA1c 5.7% to 6.4%, fasting plasma glucose 100-125 mg/dL, or 2-hour plasma glucose 140-199 mg/dL following a 75g oral glucose tolerance test),
body mass index (BMI) of at least 24 kg/m² (or 22 kg/m² for Asian Americans),
willingness to comply with all aspects of the study protocol, including attending coaching sessions and using CGM devices.

Exclusion Criteria4

Individuals will be excluded from the study if they
have a diagnosis of type 1 or type 2 diabetes,
are currently using CGMs or have medical contraindications to CGM use, such as severe skin allergies or implantable defibrillators, or
are currently enrolled in another clinical trial for prediabetes. Additionally, using validated assessments, we will exclude participants with significant dementia, alcohol or drug abuse/dependency, active psychosis, or life expectancy less than 12 months as these conditions are likely to interfere with adherence to the intervention.

Interested in this trial?

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