Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion
Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion to Minimize Re-intubation Rate: a Randomized Controlled Trial
Cairo University
200 participants
Sep 1, 2025
INTERVENTIONAL
Conditions
Summary
Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.
Eligibility
Inclusion Criteria1
- critically ill patient mechanically ventilated for 24 hours or more first spontaneous breathing trial
Exclusion Criteria1
- patient refusal difficult ultrasound views tracheostomized patient neuromuscular disorders
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Interventions
Parasternal intercostal thickening fraction less than 6.5%
Ultrasound assessment only for purpose of blinding
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07143695