RecruitingNCT07144683

Anastomotic Leakage After Colorectal Surgery.

Risk Factors for Anastomotic Leakage After Colorectal Surgery.


Sponsor

Minia University

Enrollment

430 participants

Start Date

Aug 25, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL, determine its incidence and impact on outcomes, and develop a predictive model. Approximately 430 patients undergoing colorectal resection with anastomosis will be enrolled from August 2025 to August 2026. Risk factors will be assessed preoperatively, intraoperatively, and postoperatively. AL will be defined and graded per the International Study Group of Rectal Cancer (ISGRC) criteria.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting information about patients who develop an anastomotic leak after colorectal surgery — a serious complication where the connection between two sections of the bowel leaks. Researchers want to better understand what causes this complication and how it can be prevented or treated. **You may be eligible if...** - You are 18 years or older - You are having elective or emergency colorectal (bowel) surgery where the two ends of the bowel will be joined (anastomosis) - You are able to provide written informed consent **You may NOT be eligible if...** - You are having surgery where no bowel connection is made (e.g., you will have a permanent stoma/bag) - You have inflammatory bowel disease (Crohn's disease or ulcerative colitis) - You have had previous colorectal surgery that involved a bowel connection - You are pregnant - You are unable to give informed consent or follow up after surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPatients Undergoing Colorectal Resection with Anastomosis

All eligible patients undergoing elective/emergency colorectal surgery with primary anastomosis (e.g., ileocolic, colocolic, colorectal, or coloanal)


Locations(1)

Minia University Hospital

Minya, Minya Governorate, Egypt

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NCT07144683


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