RecruitingNCT07154186
Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients
Impact of Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients
Sponsor
Sohag University
Enrollment
180 participants
Start Date
Sep 4, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Age ≥18 years old.
- Both sexes.
- Non-diabetic patients \[no history of diabetes, hemoglobin A1C (HbA1C) < 6.5%, fasting glucose < 126 mg/dL\].
- Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.
Exclusion Criteria5
- Known diabetes mellitus (type 1 or type 2).
- Previous history of coronary revascularization.
- Severe hepatic or renal dysfunction \[alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)< 30 mL/min/1.73 m²\].
- Malignant disease, autoimmune disease, or systemic inflammatory disorders.
- Current use of triglyceride-lowering medications.
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Interventions
OTHERCoronary Angiographic Assessment
Coronary angiographic assessment will be performed for all patients.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07154186
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