RecruitingNCT07154186

Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients

Impact of Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients

Sponsor

Sohag University

Enrollment

180 participants

Start Date

Sep 4, 2025

Study Type

OBSERVATIONAL

Conditions

Coronary Artery Disease Non-Diabetic Premature Triglycerides Glucose Index Angiographic Profiling

Summary

This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age ≥18 years old.
Both sexes.
Non-diabetic patients \[no history of diabetes, hemoglobin A1C (HbA1C) < 6.5%, fasting glucose < 126 mg/dL\].
Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.

Exclusion Criteria5

Known diabetes mellitus (type 1 or type 2).
Previous history of coronary revascularization.
Severe hepatic or renal dysfunction \[alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)< 30 mL/min/1.73 m²\].
Malignant disease, autoimmune disease, or systemic inflammatory disorders.
Current use of triglyceride-lowering medications.

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