"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")
Role of Topical Application of Lignocaine Versus 0.2% Glyceryl Trinitrate (GTN) Ointment as a Postoperative Local Analgesic in Hemorrhoidectomy in Terms of Pain Score,Wound Healing Time and Patient Satisfaction Level
King Edward Medical University
64 participants
Aug 2, 2025
INTERVENTIONAL
Conditions
Summary
This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl Trinitrate (GTN) ointment in reducing postoperative pain following hemorrhoidectomy. Patients undergoing hemorrhoidectomy will be randomly assigned to receive either Lignocaine ointment or GTN ointment applied locally after surgery. Pain relief will be assessed using a visual analog scale (VAS) at regular intervals during the postoperative period. The study aims to determine which ointment provides better pain control and improves patient comfort during recovery.
Eligibility
Inclusion Criteria4
- Age between 18 - 60 years
- Both genders
- Grade III and IV hemorrhoids diagnosed on the basis of history and clinical examination by consultant Surgeon.(Grade III Hemorrhoid manually reduced by patient with finger and Grade IV is prolapsed)
- ASA (American society of Anesthesia) grades I, and II
Exclusion Criteria5
- Previously reported allergy or reaction to lignocaine and GTN
- Pregnancy or lactation
- Concomitant perianal pathology warranting surgery
- Cardiovascular disease
- Patient taking Nitrates or Calcium channel blocker
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Interventions
Applied to the anal wound three time daily after hemorrhoidectomy.
Applied to the anal wound three time daily after hemorrhoidectomy.
Locations(1)
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NCT07159334