Hemorrhoid Clinical Trials

30 recruitingLast updated: May 21, 2026

There are 30 actively recruiting hemorrhoid clinical trials across 15 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3. Top locations include Nanjing, Jiangsu, China, Los Angeles, California, United States, Bellinzona, Switzerland. Updated daily from ClinicalTrials.gov.


Hemorrhoid Trials at a Glance

30 actively recruiting trials for hemorrhoid are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Nanjing, Los Angeles, and Bellinzona. Lead sponsors running hemorrhoid studies include Andrea Saporito, Aydin Adnan Menderes University, and Ain Shams University.

Browse hemorrhoid trials by phase

About Hemorrhoid Clinical Trials

Looking for clinical trials for Hemorrhoid? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hemorrhoid trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hemorrhoid clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting
Not Applicable

SHAPE Versus Milligan-Morgan Hemorrhoidectomy for Hemorrhoidal Disease

Hemorrhoid
Cairo University68 enrolled1 locationNCT07598630
Recruiting
Not Applicable

Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

HAEHemorrhoids, InternalHemorrhoidal Bleeding+1 more
Jessica K. Stewart, MD40 enrolled1 locationNCT07559630
Recruiting

HEMOVAR Study on Hemorrhoids and Varicose Veins

HemorrhoidsVaricose Veins of Lower Limb
Aydin Adnan Menderes University400 enrolled1 locationNCT07317492
Recruiting
Not Applicable

Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in Hemorrhoidectomy

Postoperative PainHemorrhoidsPerioperative Anxiety
Yuzuncu Yil University90 enrolled1 locationNCT06860100
Recruiting
Phase 4

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Hemorrhoids
University of Oklahoma100 enrolled1 locationNCT04248205
Recruiting
Not Applicable

PUSHES (Pudendal Block Versus Sacral ESP Hemorrhoidectomy Study)

HemorrhoidsHemorrhoids Third Degree
Andrea Saporito64 enrolled1 locationNCT07350460
Recruiting
Phase 2

Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain

Postoperative PainHemorrhoids
Lomonosov Moscow State University Medical Research and Educational Center292 enrolled1 locationNCT07399860
Recruiting
Not Applicable

The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery

Pain ManagementLocal InfiltrationHemorrhoid Surgery+1 more
Beijing Tiantan Hospital156 enrolled1 locationNCT07442539
Recruiting
Not Applicable

Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)

Internal HemorrhoidsHAE
University of California, Los Angeles22 enrolled1 locationNCT07179601
Recruiting

Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease

Hemorrhoid BleedingHemorrhoids ProlapseHemorrhoid Pain+2 more
Cardarelli Hospital80 enrolled1 locationNCT07295886
Recruiting
Not Applicable

Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease

Hemorrhoids
Universitair Ziekenhuis Brussel80 enrolled1 locationNCT05697562
Recruiting
Not Applicable

Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy

Hemorrhoids
Ain Shams University50 enrolled1 locationNCT06969274
Recruiting
Not Applicable

"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")

Postoperative PainHemorrhoid
King Edward Medical University64 enrolled1 locationNCT07159334
Recruiting
Not Applicable

Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids

Hemorrhoids
University Hospitals of North Midlands NHS Trust20 enrolled1 locationNCT06175325
Recruiting
Phase 4

Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With Hemorrhoids

Hemorrhoid
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey250 enrolled1 locationNCT07128979
Recruiting

Effectiveness of Pudendal Nerve Block in reducing Post-Op Pain after Proctological Interventions in patients aged 18 to 70 years old

AnesthesiaHemorrhoidsPerianal Fistula
Combined Military Hospital Tamiz ud din road Rawalpindi Pakistan 4600096 enrolled1 locationACTRN12625000850471
Recruiting
Not Applicable

Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery

Musical TherapyHemorrhoidAnal Fistulas+1 more
Clinique Saint-Vincent550 enrolled2 locationsNCT06798155
Recruiting

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

Internal Hemorrhoid
Mayo Clinic20 enrolled1 locationNCT06106269
Recruiting

ORal Aminaphtone and Combined LidocainE

Hemorrhoid
Treviso Regional Hospital50 enrolled1 locationNCT07026513
Recruiting

Cough and Hemorrhoids

CoughCough FrequencyCough Severity+3 more
Muğla Sıtkı Koçman University134 enrolled1 locationNCT06878209