RecruitingNot ApplicableNCT07177989

Combined Effects of Alternate Nostril Breathing and Aerobic Interval Training on Blood Pressure and Heart Rate Products in Patients With Hypertension

Sponsor

Foundation University Islamabad

Enrollment

36 participants

Start Date

Jan 15, 2025

Study Type

INTERVENTIONAL

Conditions

Hypertension (HTN)

Summary

Hypertension (HTN) is the foremost preventable risk factor for cardiovascular disease (CVD) and all-cause mortality, contributing to over 7 million deaths annually within the nearly 17 million attributed to CVD. Effective management through lifestyle modifications, including aerobic exercises specifically interval training presents a promising avenue for blood pressure regulation by promoting vasodilation and regulating the autonomic nervous system. Likewise, alternate nostril breathing has demonstrated efficacy in lowering blood pressure by optimizing oxygenation and improving endothelial function but their combined effect on BP measures is yet to be determined. Hence this study aims to determine the combined effects of aerobic interval training with and without alternate nostril breathing on blood pressure, rate pressure product and quality of life in patients with hypertension.

Eligibility

Min Age: 25 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether combining alternate nostril breathing (a yogic breathing technique) with aerobic interval training can help lower blood pressure and reduce the workload on the heart in adults with hypertension (high blood pressure). **You may be eligible if...** - You are between 25 and 50 years old - You have been diagnosed with Stage 1 hypertension (blood pressure 130-139/80-89 mmHg) or Stage 2 hypertension (blood pressure 140/90 mmHg or higher) per AHA/ACC 2017 guidelines - You are able to understand and follow the exercise and breathing instructions **You may NOT be eligible if...** - You have an active infection - You have a musculoskeletal or neurological condition that prevents physical activity - You are an active smoker - You have any contraindication to exercise testing or training - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERExperimental Group

The interventional group will perform aerobic training (stationary cycling) 3 days a week for 5 weeks, starting with 40-60% heart rate reserve (HRR) for 20-30 minutes, with thein the first week and increasing to 40-85% HRR, maintaining a target heart rate of 40-60% HRR at the lower end and 75-85% HRR at the upper end, following a 1:4 work-to-rest ratio for 30-40 minutes in subsequent weeks, with the warm up of 5 mins before the session and a cool down of 5-7 mins after every seasion. Exercise heart rate will be calculated using the Karvonen formula for the base line week and the following weeks.Following each aerobic session, they'll practice Alternate Nostril Breathing (ANB), beginning with 5 minutes in the first week and progressing to 10 minutes thereafter. ANB involves specific hand positioning and breathing techniques to promote relaxation and balance. All sessions will be supervised by a physiotherapist.

OTHERinterventional group A

In interventional group 'A' participants will perform aerobic training for 3 days a week for 30-40 minutes a day for 5 consecutive weeks. Exercise heart rate will be calculated using the Karvonen formula. For the first base line week the aerobic session begins with a 5-minute warm-up. The primary cardiovascular component involves using a cycle ergometer (stationary cycling) at an intensity of 40-60% heart rate reserve (HRR) for 20-30 minutes. Finally, the workout will concludes with a cool-down phase lasting 5-7 minutes, allowing the heart rate to gradually return to baseline and preventing post-exercise hypotension. From the second week onwards, the aerobic training session will begin with a 5-minute warm-up to prepare the body and gradually increase heart rate. The main workout involves a cycle ergometer, maintaining a target heart rate of 40-60% HRR at the lower end and 75-85% HRR at the upper end, following a 1:4 work-to-rest ratio for 30-40 minutes. The session ends with a 5-7 min