RecruitingPhase 2NCT07182526

Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome

Impact of Adding Quercetin or Alpha Lipoic Acid as an Adjuvant Therapy on Clinical and Biochemical Outcomes in a Sample of Iraqi PCOS Patients

Sponsor

Al-Mustansiriyah University

Enrollment

150 participants

Start Date

Sep 20, 2025

Study Type

INTERVENTIONAL

Conditions

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Summary

This study will investigate whether the addition of Quercetin or Alpha-Lipoic Acid (ALA) to standard metformin therapy can improve symptoms, hormone levels, metabolic health, and quality of life in women with polycystic ovary syndrome (PCOS). Over 3 months, participants will be randomly assigned to one of three groups: metformin alone, metformin plus Quercetin, or metformin plus ALA. Researchers will measure changes in hormones, blood sugar, cholesterol, and antioxidant markers, as well as quality of life and medication adherence. Physical measurements and side effects will also be recorded to assess safety and overall benefit.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding quercetin or alpha-lipoic acid (both natural antioxidants) to standard care can help manage symptoms in women newly diagnosed with polycystic ovary syndrome (PCOS). PCOS is a hormonal condition that can cause irregular periods, excess hair growth, and fertility difficulties. **You may be eligible if...** - You are a woman between 18 and 40 years old - You have been newly diagnosed with PCOS - You have irregular periods (cycles longer than 35 days) - Your ultrasound shows polycystic ovaries - You have signs of excess androgen (male hormone), such as acne or excess hair growth **You may NOT be eligible if...** - You have adrenal gland disorders, diabetes, high blood pressure, or other hormonal conditions - You have used oral contraceptives, hormonal therapy, or cholesterol-lowering medications recently - You are currently pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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