RecruitingNot ApplicableNCT07183423

Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction

A Pilot Double-Blind Randomized Controlled Trial on the Efficacy and Safety of a Novel Skin Barrier Product Versus Petrolatum in Individuals With Skin Barrier Dysfunction


Sponsor

Makati Medical Center

Enrollment

26 participants

Start Date

Aug 31, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. The main questions it aims to answer are: Does the novel barrier topical product improve skin hydration, skin sebum, redness, and pigmentation? Does it improve subjective dryness and itch? Researchers will compare the novel barrier topical product to petrolatum (a gold standard occlusive barrier repair agent) to see how they are comparable in treating skin barrier dysfunction. Participants will: Apply the novel barrier topical product or petrolatum twice a day for 28 days Visit the clinic once a week for checkups and tests Keep a diary of their application of the assigned product


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Novel barrier repair topical product and Petrolatum for people with atopic dermatitis, contact dermatitis, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNovel barrier repair topical product

Novel barrier product (containing ceramide, virgin coconut oil, cholesterol)

OTHERPetrolatum

Petrolatum application


Locations(1)

VMV Skin Research Center & Clinics

Makati City, National Capital Region, Philippines

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NCT07183423


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