RecruitingNCT07185100

Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR

A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR


Sponsor

German Heart Institute

Enrollment

600 participants

Start Date

Sep 13, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Heart failure (HF) in patients at risk is often overlooked, and when detected, there is a lack of early and effective preventive interventions. The WE-CARE-HF-CMR study, conducted in large cities/metropol areas in Germany ( \> 1.000.000 inhabitants), aims to close this gap by evaluating the feasibility of a mobile, telemedicinemonitored HF-screening approach combining cardiac magnetic resonance imaging (CMR), quality of life assessment and laboratory tests as key elements in asymptomatic patients at risk. WE-CARE-HF-CMR will provide a proposal for a comprehensive, contemporary screening approach for patients at risk to develop HF tailored to the needs of the target population. This will provide important new information on the prevalence of asymptomatic HF in at-risk patients in urban versus rural areas. The results of the study will be compared with the results from the "HERZCheck'' trial, which provides data from approximately 4,500 participants in rural areas in Germany and has already been completed (NCT05122793).


Eligibility

Min Age: 40 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This study is using a special heart MRI scan (cardiac MRI) to check for undiagnosed heart failure in people who are at higher risk because of conditions like diabetes, high blood pressure, high cholesterol, or obesity, but who don't have obvious heart failure symptoms yet. It is being conducted in urban areas across Germany. **You may be eligible if...** - You are 40–69 years old - You have one or more risk factors: diabetes, high blood pressure, high cholesterol, obesity (BMI over 30), kidney disease, or smoking history - You have no current diagnosis of heart failure **You may NOT be eligible if...** - You have already been diagnosed with heart failure or reduced heart pumping function - You have a pacemaker, defibrillator, or other metal implants that make MRI unsafe - You are claustrophobic or have severe hearing loss - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Deutsches Herzzentrum der Charité

Berlin, Germany

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NCT07185100


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