Cancer-related Fatigue and Its Biological Contributors in Adolescent and Young Adult Brain Tumor Survivors: Effects of a Tele-exercise Intervention

This study is testing an online (telehealth) exercise program for young adult survivors of brain tumors (aged 18–39) who continue to feel extreme tiredness (cancer-related fatigue) after completing their treatment. The goal is to see if regular exercise reduces fatigue and improves quality of life. **You may be eligible if...** - You are aged 18–39 and your brain tumor was diagnosed between ages 15–39 - You finished cancer treatment (including both chemotherapy and radiation) 6 months to 5 years ago - You have significant fatigue based on a standard questionnaire - You are currently not doing much exercise (under 150 minutes per week) - You can speak, write, and read English **You may NOT be eligible if...** - You have an unstable heart or lung condition that makes exercise unsafe - You have had a recent fracture or injury preventing exercise - You have recurring disease or require re-irradiation of the brain - You have significant cognitive or sensory impairments Talk to your doctor to see if this trial is right for you.