Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients
Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients: a Randomized Controlled Trial
Deraya University
20 participants
Jul 10, 2025
INTERVENTIONAL
Conditions
Summary
Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients
Eligibility
Inclusion Criteria4
- Their age\< 35 up to 50 years old
- Both sexes.
- Controlled HTN ( stage 1,B.P 140-159 mmhg / 90-99 mmhg and stage 2, B.P 160-179 mmhg-100-109 mmhg )
- Hemodynamic stable. Able to provide informed consent
Exclusion Criteria7
- Uncontrolled hypertension.
- Severe HTN \<180/110 mmhg
- Renal dysfunction
- Unstable cardiac conditions
- Severe pulmonary disease that limit exercise
- Impaired cognition
- Musculoskeletal problems that made it difficult to do exercise
Interventions
Eating vegetables, fruits, and whole grains Including fat-free or low-fat dairy products, fish, poultry, beans, nuts, and vegetable oils Limiting foods that are high in saturated fat, such as fatty meats, full-fat dairy products, and tropical oils such as coconut, palm kernel, and palm oils Limiting sugar-sweetened beverages and sweets
High Intensity Interval Training
Locations(1)
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NCT07188272