Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients
The Clinical Efficacy of Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients
Northern Jiangsu People's Hospital
30 participants
Sep 24, 2025
INTERVENTIONAL
Conditions
Summary
In this study,the researchers compared the changes in immune function-related indicators in patients with liver cirrhosis following laparoscopic partial splenectomy,to determine whether this surgical intervention can enhance postoperative immune function and thereby improve patient outcomes.
Eligibility
Inclusion Criteria4
- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
- Splenomegaly with secondary hypersplenism
- gastroesophageal variceal bleeding
- Informed consent to participate in the study
Exclusion Criteria7
- Hepatocellular carcinoma or any other malignancy,
- Child-Pugh grade C
- Recent peptic ulcer disease
- History of Hemorrhagic stroke
- Pregnancy.
- Uncontrolled Hypertension
- Human immunodeficiency virus (HIV) infection
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Interventions
The laparoscopic partial splenectomy technique involved preserving the short gastric vessels and the splenic suspensory ligament, with resection conducted along the demarcation line.
Locations(1)
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NCT07205471