The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients

This study examines the effects of laparoscopic (minimally invasive) splenectomy and disconnection of abnormal blood vessels (azygoportal disconnection) in patients with portal hypertension — high blood pressure in the liver's vein system — caused by liver disease. **You may be eligible if...** - You have portal hypertension with an enlarged spleen (hypersplenism) - You are scheduled for laparoscopic splenectomy with azygoportal disconnection - You are 18 or older - You consent to participate and to follow-up assessments **You may NOT be eligible if...** - Your liver function is too poor for surgery (Child-Pugh C or severe) - You have had prior major abdominal surgery preventing laparoscopic access - You are pregnant Talk to your doctor to see if this trial is right for you.