RecruitingNot ApplicableNCT05325437
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients
Sponsor
Northern Jiangsu People's Hospital
Enrollment
20 participants
Start Date
Mar 1, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
- Splenomegaly with secondary hypersplenism
- gastroesophageal variceal bleeding
- Informed consent to participate in the study
Exclusion Criteria7
- Hepatocellular carcinoma or any other malignancy,
- Child-Pugh grade C
- Recent peptic ulcer disease
- History of Hemorrhagic stroke
- Pregnancy.
- Uncontrolled Hypertension
- Human immunodeficiency virus (HIV) infection
Interventions
PROCEDURELaparoscopic splenectomy and azygoportal disconnection
The laparoscopic splenectomy and azygoportal disconnection was performed by the same surgical team.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05325437
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