RecruitingNot ApplicableNCT07211529

Intraoperative Paravertebral Block and Postoperative Complications

Perioperative Paravertebral Block Reduces Postoperative Complications in Thoracic Surgery: An Observational Study

Sponsor

Tongji Hospital

Enrollment

500 participants

Start Date

Mar 25, 2025

Study Type

INTERVENTIONAL

Conditions

Lung Cancer (Diagnosis)Video-assisted Thoracoscopic Surgery (VATS)Pulmonary Infections Respiratory Failure Without Hypercapnia Pleural Effusion Due to Another Disorder (Disorder)Atelectasis Bronchospasm Pneumothorax Pulmonary Embolism (Diagnosis)Bronchopleural Fistula Acute Respiratory Distress Syndrome (ARDS)

Summary

This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether performing a paravertebral nerve block (an injection of local anesthetic near the spine) during minimally invasive chest surgery reduces post-surgical complications such as pain, pneumonia, or other lung problems. **You may be eligible if...** - You are 18 or older - You are scheduled for lung surgery using a keyhole (VATS or RATS) approach, including wedge resection, segmentectomy, lobectomy, or mediastinal surgery - You can provide informed consent **You may NOT be eligible if...** - You refuse consent - You have had prior chest surgery on the same side - Your surgery is converted to open thoracotomy during the procedure - You are lost to follow-up or refuse post-operative assessments Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREParavertebral Block (PVB)

Participants in this arm will receive a paravertebral nerve block (PVB) performed intraoperatively under ultrasound guidance prior to the thoracic surgical procedure. The block will target the relevant thoracic vertebral levels corresponding to the surgical site. Standard local anesthetic agents will be administered according to institutional protocols. This intervention aims to provide perioperative analgesia, reduce postoperative pain, and potentially decrease the incidence of postoperative complications. All participants will also receive standard intraoperative monitoring and anesthesia management as per routine clinical practice.

Locations(1)

Tongji Medical College of HUST: Huazhong University of Science and Technology Tongji Medical College Tongji Hospital

Wuhan, Hubei, China

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NCT07211529

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