RecruitingNot ApplicableNCT07211529

Intraoperative Paravertebral Block and Postoperative Complications

Perioperative Paravertebral Block Reduces Postoperative Complications in Thoracic Surgery: An Observational Study


Sponsor

Tongji Hospital

Enrollment

500 participants

Start Date

Mar 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • Male or female participants aged 18 years or older.
  • Scheduled to undergo thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS) or Robotic-Assisted Thoracoscopic Surgery (RATS), including wedge resection, segmentectomy, lobectomy, or mediastinal surgery.
  • Signed informed consent obtained prior to study participation. -

Exclusion Criteria6

  • Patients who refuse to provide informed consent.
  • Anesthesiologists who have not received training in ultrasound-guided paravertebral block (PVB-US).
  • History of ipsilateral thoracic surgery.
  • Conversion to open thoracotomy during the procedure.
  • Patients who did not complete the scheduled surgery due to disease progression or medical reasons.
  • Patients who are lost to follow-up or refuse postoperative follow-up. -

Interventions

PROCEDUREParavertebral Block (PVB)

Participants in this arm will receive a paravertebral nerve block (PVB) performed intraoperatively under ultrasound guidance prior to the thoracic surgical procedure. The block will target the relevant thoracic vertebral levels corresponding to the surgical site. Standard local anesthetic agents will be administered according to institutional protocols. This intervention aims to provide perioperative analgesia, reduce postoperative pain, and potentially decrease the incidence of postoperative complications. All participants will also receive standard intraoperative monitoring and anesthesia management as per routine clinical practice.


Locations(1)

Tongji Medical College of HUST: Huazhong University of Science and Technology Tongji Medical College Tongji Hospital

Wuhan, Hubei, China

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NCT07211529


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