US Benchmarking Clinical Study

This US benchmarking study is collecting heart measurements using ultrasound in three groups of people aged 60 and over: those with heart failure with preserved pumping function (HFpEF), those with the same condition plus a protein deposit disease called ATTR cardiomyopathy, and healthy controls. The goal is to test and validate new ultrasound measurement technology. **You may be eligible if...** - You are 60 years of age or older - For heart failure groups: You meet criteria for heart failure with preserved ejection fraction, with or without a confirmed ATTR cardiomyopathy diagnosis - For the control group: You have no diagnosis of heart failure or cardiomyopathy **You may NOT be eligible if...** - You are pregnant or pre-menopausal - You have had a heart attack in the past 30 days or have an uncontrolled fast heart rate - You have a mechanical heart valve or cardiac assist device - You have severe kidney disease (on dialysis or near-dialysis) - You have moderate or severe liver disease - You have had a heart, lung, liver, or kidney transplant - You have certain heart abnormalities, such as irregular heart rhythm at the time of measurement or severe valve disease from non-ATTR causes Talk to your doctor to see if this trial is right for you.