HFpEF - Heart Failure With Preserved Ejection Fraction Clinical Trials

14 recruiting

Frequently Asked Questions

Common questions about HFpEF - Heart Failure With Preserved Ejection Fraction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Not Applicable

Can Tiny Bubbles Offer an Alternative to Catheters for Assessing Pressures Inside the Heart? Investigating Ultrasound Contrast Agents as Pressure Sensors Against Gold Standard Catheter Pressures in Cardiac Catheterisation Patients.

Heart DiseaseHFpEF - Heart Failure With Preserved Ejection FractionCardiac Catheterisation
King's College London10 enrolled1 locationNCT07416279
Recruiting
Phase 2

Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension

HFrEF - Heart Failure With Reduced Ejection FractionHFpEF - Heart Failure With Preserved Ejection FractionGroup 2 Pulmonary Hypertension
Salubris Biotherapeutics Inc30 enrolled1 locationNCT07221513
Recruiting
Not Applicable

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

HFpEF - Heart Failure With Preserved Ejection Fraction
University of Nebraska300 enrolled3 locationsNCT05784753
Recruiting
Not Applicable

AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure

Atrial FibrillationHFpEF - Heart Failure With Preserved Ejection Fraction
Technical University of Munich40 enrolled1 locationNCT06650995
Recruiting
Phase 2Phase 3

Tailored Exercise Training Study Among Adults With HFpEF

Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting

US Benchmarking Clinical Study

Cardiac AmyloidosisHFpEF - Heart Failure With Preserved Ejection FractionHFmrEF+2 more
eMyosound SAS150 enrolled3 locationsNCT07215715
Recruiting
Phase 2

CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation

HFpEF - Heart Failure With Preserved Ejection FractionFontan CirculationSingle Ventricle Heart Disease
Mayo Clinic27 enrolled1 locationNCT06762964
Recruiting
Not Applicable

MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

HFpEF - Heart Failure With Preserved Ejection Fraction
University of Pennsylvania270 enrolled1 locationNCT06670001
Recruiting
Phase 1Phase 2

Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

HFpEF - Heart Failure With Preserved Ejection FractionColchicine
I.M. Sechenov First Moscow State Medical University40 enrolled2 locationsNCT05637398
Recruiting

Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences

Heart FailureDiabetes Mellitus, Type 2HFrEF - Heart Failure With Reduced Ejection Fraction+1 more
University of Leeds600 enrolled1 locationNCT06774014
Recruiting

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Heart FailureCardiotoxicityMyocardial Infarction+12 more
Peerbridge Health, Inc1,500 enrolled8 locationsNCT06699056
Recruiting

Exercise Magnetic Resonance Imaging in Patients With Obesity Associated Heart Failure

HFpEF - Heart Failure With Preserved Ejection Fraction
University Medical Center Groningen50 enrolled1 locationNCT06514820
Recruiting

Validation of a Machine Learning Predictive Model to Distinguish Post-capillary Pulmonary Hypertension

Pulmonary HypertensionPulmonary Arterial HypertensionHFpEF - Heart Failure With Preserved Ejection Fraction
KU Leuven100 enrolled4 locationsNCT06405126
Recruiting
Not Applicable

Catheter Ablation in Atrial Fibrillation Patients With HFpEF (STABLE-SR IV Trial)

Atrial FibrillationHFpEF - Heart Failure With Preserved Ejection Fraction
The First Affiliated Hospital with Nanjing Medical University436 enrolled1 locationNCT06125925