RecruitingNCT07216053

Predictive Value of Lung Ultrasound for Respiratory Decompensation in Late Preterm Neonates


Sponsor

Hackensack Meridian Health

Enrollment

300 participants

Start Date

Nov 6, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Respiratory morbidity presents a significant clinical challenge in the neonatal period, and an individual patient's clinical course is often difficult to predict. This is especially true for late-preterm infants, who share some of the same risks of premature babies in terms or respiratory morbidity, but whose births may not always be attended by a neonatologist, or who may be born at hospitals with lower level Neonatal Intensive Care Units (NICUs) and require transfer if they decompensate. With this study, the aim is to 1) determine the efficacy of early point of care lung ultrasound (LUS) to predict respiratory decompensation in the first 48 hours of life in late preterm infants and 2) to compare the performance of three lung ultrasound scoring systems, 3 type-of-lung, high risk pattern and total LUS scoring systems.


Eligibility

Min Age: 34 WeeksMax Age: 36 Weeks

Inclusion Criteria3

  • Inborn infants born between 34w0d and 36w6d gestational age
  • In RA or 1 Litre per minute 1LPM NC (room air (RA) or nasal cannula (NC))
  • Admitted to NICU or Well Baby Nursery (WBN)

Exclusion Criteria5

  • Patients born \<34 weeks or \>36w6d
  • Major genetic anomaly or syndromic condition
  • Cardiac or pulmonary structural defects
  • Cord pH \<7.0 or 5 minute APGAR 5 or less
  • Suspected fetal hemorrhage or other source of significant anemia at birth

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Interventions

DIAGNOSTIC_TESTPoint of care lung ultrasound

Point-of-care lung ultrasound (POC LUS) in their first 4 hours of life and be scored based on three established scoring systems


Locations(1)

Hackensack Univeristy Medical Center

Hackensack, New Jersey, United States

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NCT07216053


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