RecruitingNot ApplicableNCT06812507

Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile

Evaluation of Placental Transfusion Techniques in of Prematurity Related Complications and Hematological Profile


Sponsor

Alexandria University

Enrollment

160 participants

Start Date

Mar 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in premature neonates over the first days of life


Eligibility

Min Age: 1 MinuteMax Age: 2 Minutes

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Delayed cord clamping, a procedure called cut umbilical milking, and others for people with placental transfusion and premature. The study is currently recruiting participants at 1 location. People eligible for this study include aged 1 Minute to 2 Minutes.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREintact umbilical milking

Umbilical cord milking will be performed by holding the newborn at or ∼20 cm below the level of the placenta. The cord will be pinched between 2 fingers as close to the placenta as possible and milked toward the infant over a 2-second duration. The cord will then be released and allowed to refill with blood for a brief 1- to 2-second pause between each milking motion. This will be repeated for 2-4 times. After completion, the cord will be clamped, and the neonate will be handed to the resuscitation team.

PROCEDUREcut umbilical milking

Another technique, used more often in Asia, involves clamping and cutting a long segment of the umbilical cord immediately at birth and passing the baby and the long cord to the pediatric provider, called C-UCM untwists the cord and milks the entire contents into the baby. Milking the cord 2-3 times before clamping may produce a similar placental transfusion as C-UCM

PROCEDUREDelayed cord clamping

Infants placed on the maternal abdomen or at the introitus below the level of placenta and waiting at least 30- to 60-second before clamping the cord.


Locations(1)

Marwa Mohamed Farag

Alexandria, Egypt

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NCT06812507


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