RecruitingPhase 1NCT07219589

A Single and Multiple Ascending Dose Study of HM17321 in Healthy and Obese Participants

A Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM17321 in Healthy and Obese Participants


Sponsor

Hanmi Pharmaceutical Company Limited

Enrollment

90 participants

Start Date

Nov 6, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a Phase 1 study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of HM17321 after single and multiple ascending doses in healthy and obese participants.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called HM17321 and a drug called Placebo of HM17321 for people with obese and obesity. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHM17321

Participants will receive a single or multiple subcutaneous injections of HM17321 at the assigned dose level. HM17321 is provided as a sterile solution in prefilled syringes.

DRUGPlacebo of HM17321

Participants will receive a single or multiple subcutaneous injections of a matching placebo solution in prefilled syringes. The placebo does not contain any active ingredients.


Locations(1)

Medpace Clinical Pharmacology Unit

Cincinnati, Ohio, United States

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NCT07219589


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