Obese Clinical Trials

5 recruiting

Frequently Asked Questions

Common questions about Obese clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients

Esophageal CancerGastric CancerHypoxemia+1 more
Zhejiang University410 enrolled5 locationsNCT07175155
Recruiting
Not Applicable

NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status

MDDObese Adults
National Science and Technology Council, Taiwan50 enrolled1 locationNCT07439744
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled2 locationsNCT06845202
Recruiting
Phase 1

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

Overweight or Obese AdultsOverweight or Obese, Type 2 Diabetes
Alveus Therapeutics, Inc.180 enrolled1 locationNCT07399678
Recruiting
Phase 2

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

ObesityWeight LossObese+1 more
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics50 enrolled17 locationsNCT07400588
Recruiting
Not Applicable

KETO-TUMOR: a Study on Brain Tumors and Central Obesity

Obese PatientsHypothalamic Neoplasms
Meyer Children's Hospital IRCCS30 enrolled1 locationNCT07396896
Recruiting

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Insulin ResistanceCognitive DeclineInflammation+8 more
Washington University School of Medicine117 enrolled2 locationsNCT05277558
Recruiting
Not Applicable

Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.

Diabetes Mellitus Type 2 in Obese
University Hospital, Lille396 enrolled4 locationsNCT03821636
Recruiting
Phase 2Phase 3

A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction

Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Early Phase 1

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

ObesityMultiple SclerosisLong COVID+4 more
University of Chicago30 enrolled1 locationNCT06171152
Recruiting
Phase 4

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

Type 2 Diabetes Mellitus in ObeseHeart Failure With Preserved Ejection Fraction
The University of Texas Health Science Center at San Antonio78 enrolled1 locationNCT05838287
Recruiting
Phase 3

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

ObesePCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
University of Colorado, Denver80 enrolled1 locationNCT05819853
Recruiting
Phase 2Phase 3

Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma

Endometrial CarcinomaOverweightObese+1 more
Xiaojun Chen89 enrolled1 locationNCT05316467
Recruiting
Not Applicable

Therapeutic Potential of a Synbiotic to Improve Mental Health in Subjects With Obesity.

Depressive DisorderAnxietyObese Patients (BMI ≥ 30 kg/m²)
Celia Bañuls120 enrolled1 locationNCT06901739
Recruiting
Not Applicable

Remission of Type 2 Diabetes With Lifestyle Intervention

Diabetes Mellitus, Type 2Obese Diabetics
University of Split, School of Medicine120 enrolled1 locationNCT07017127
Recruiting
Not Applicable

Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux

Barrett EsophagusObese PatientsTobacco Use+2 more
Louis Stokes VA Medical Center400 enrolled1 locationNCT06746623
Recruiting

Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

Obesity, ChildhoodType 2 Diabetes Mellitus in Obese
Philippe Klee, MD-PhD50 enrolled1 locationNCT06682481
Recruiting
Not Applicable

Exercise-snacks for Breaking the Sedentary Lifestyle and Improving the Physical Fitness of Obese Adolescents?

ExerciseObese AdolescentsSedentary Time
University of Avignon36 enrolled2 locationsNCT06626295
Recruiting
Phase 2

The Effects of the GOLO for Life® Plan With Release Supplement on Glycemic Control and Weight in Overweight and Obese Adults With Prediabetes or Type 2 Diabetes

OverweightPrediabetesType 2 Diabetes+1 more
Golo100 enrolled2 locationsNCT05844644
Recruiting
Not Applicable

Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction

Diabetes Mellitus Type 2 in Obese
Region Stockholm286 enrolled1 locationNCT05801614