RecruitingNot ApplicableNCT07223853

AI-driven Clinical Decision Support for Perioperative Blood Orders

Intelligent Clinical Decision Support for Preoperative Blood Management: A Cluster-Randomized Clinical Trial


Sponsor

Washington University School of Medicine

Enrollment

50 participants

Start Date

Oct 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion. Presurgical preparation for transfusion is important to allow for safe and timely transfusion during surgery; however, excessive preparation is unfortunately common, costly, and contributes to blood waste. This study aims to evaluate an intelligent clinical decision support system that helps clinicians prepare blood for patients who are likely to need it, while avoiding excessive preparation for patients who don't, potentially improving patient safety while reducing blood waste and healthcare costs.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Scheduled for surgery in one of the main operating room areas (non-remote) at Barnes Jewish Hospital
  • Evaluated in-person at one of the preoperative assessment clinics affiliated with BJC Healthcare
  • Have a valid S-PATH model prediction prior to their preoperative assessment clinic visit

Exclusion Criteria4

  • Clinician (resident physician or advanced practice provider) who works at a preoperative assessment clinic
  • None
  • Pregnant
  • Presence or history of red cell alloantibodies

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Interventions

OTHERS-PATH clinical decision support system

Access to the S-PATH electronic health record (EHR)-integrated clinical decision support system

OTHERUsual care

Including use of the conventional Maximum Surgical Blood Ordering Schedule (MSBOS)


Locations(1)

Washington University / Barnes Jewish Hospital

St Louis, Missouri, United States

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NCT07223853


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