Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

This study evaluates two devices used together — the iStent Infinite (a tiny implant that improves fluid drainage in the eye) and iDose TR (a sustained-release medication implant) — as a standalone treatment for people with moderate to severe open-angle glaucoma who have not responded well to eye drops or laser therapy. **You may be eligible if...** - You have moderate to severe open-angle glaucoma (including primary, pigmentary, or pseudoexfoliation types) - You have tried and failed eye drop medications and/or laser treatment - Your eye's drainage angle is open (Shaffer grade ≥ 3) - Your doctor is considering surgical treatment as the next step **You may NOT be eligible if...** - You have traumatic, inflammatory (uveitic), neovascular, or angle-closure glaucoma - You have had previous incisional glaucoma surgery - You have had certain laser procedures within the past 90 days - You have active eye inflammation, significant corneal disease, or other conditions that interfere with pressure measurement Talk to your doctor to see if this trial is right for you.