Rectus-Intercostal Fascial Plane Block for Liver Transplantation Donors
Evaluation of Postoperative Analgesic Efficacy of Ultrasound-Guided Rectus-Intercostal Fascial Plane Block in Living Liver Donors
Istinye University
64 participants
Dec 22, 2025
INTERVENTIONAL
Conditions
Summary
Postoperative pain control plays a crucial role in enhancing recovery and improving early mobilization in living liver donors. The rectus-intercostal fascial plane (RIFP) block is a novel ultrasound-guided regional anesthesia technique that provides anterior abdominal wall analgesia by targeting the intercostal nerves between the rectus abdominis and intercostal muscle fascia. This prospective, randomized controlled clinical study aims to evaluate the postoperative analgesic efficacy and opioid-sparing effects of the RIFP block compared with standard intravenous analgesia in living liver donors undergoing donor hepatectomy. Participants will be randomly assigned to two groups: Group 1 (RIFP Block): Patients receiving an ultrasound-guided rectus-intercostal fascial plane block using 20 mL of 0.25% bupivacaine at the end of surgery, in addition to standard IV PCA (morphine). Group 2 (Control): Patients receiving only standard IV PCA (morphine) without regional block.
Eligibility
Inclusion Criteria3
- Age between 18 and 75 years
- Patients with American Society of Anesthesiology (ASA) physical status I-II
- Patients scheduled for a living donor hepatectomy
Exclusion Criteria7
- Allergy to local anesthetics
- Coagulopathy
- Skin infection at the block area
- Advanced renal failure
- Chronic pain syndromes
- Alcohol or drug abuse
- Psychiatric disorders
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Interventions
Rectus intercostal plane block will be administered bilaterally at the end of the surgery and after skin closure under ultrasound guidance
Ultrasound probe placement on the same region without needle insertion or local anesthetic injection to maintain blinding.
Locations(1)
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NCT07233096