RecruitingNCT07237009

Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive Disorders

Effects of Personalized Reminiscence Sessions Delivered by a Digital Conversational Agent to Patients With Neurocognitive Disorders


Sponsor

KompanionCare SAS

Enrollment

80 participants

Start Date

Oct 14, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to observe the effects of daily personalized digital reminiscence sessions, conducted with the help of a digital conversational agent, and to determine whether these sessions lead to improvements in symptoms such as apathy and depression. The researchers therefore seek to observe whether this daily use can improve certain aspects of well-being, such as motivation, mood, sleep quality, quality of life, and engagement with the tool. The study also aims to assess whether simple reminders delivered via the application are sufficient to encourage regular use without external assistance. Participants will: * Use the reminiscence app for 25 days for 10-15 minutes. * Have a primary caregiver help personalize the app by sharing family memories, other relatives may optionally contribute in a private group. * Complete brief questionnaires at the start and during follow-up routine visits (for example, apathy and depression scales, sleep, and quality of life).


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a personalized digital reminiscence therapy — a program that uses personally meaningful photos and memories on a tablet or phone — to reduce depression, apathy, and anxiety in older adults with mild cognitive impairment or early-stage dementia. **You may be eligible if...** - You are over 60 years old - You have been diagnosed with mild cognitive impairment or early-stage major neurocognitive disorder (such as early Alzheimer's) - You have a mild or moderate level of depression, apathy, or both - You have access to an Apple device (iPhone or iPad) running iOS - You can see and hear the content on the device **You may NOT be eligible if...** - You have moderate to severe dementia - You have major physical limitations that prevent you from interacting with the device - You score below 21 or above 28 on the standard MMSE memory test Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

CHU Angers, Service médecine gériatrique.

Angers, France

Limoges University Hospital Center - Dupuytren Hospital], Geriatric medicine department

Limoges, France

Centre Hospitalier Universitaire de Nice - Institut Claude Pompidou, Centre Mémoire de Ressources et de Recherches (CM2R)

Nice, France

APHP Hôpitaux universitaires Paris centre.

Paris, France

CHU DE TOURS, Pôle Vieillissement, Hôpital Bretonneau.

Tours, France

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NCT07237009


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