RecruitingNCT07237685

Evaluating Atherosclerotic Disease Progression in Patients With Diabetes Mellitus

Evaluating Atherosclerotic Disease Progression in High-Risk Patients With Diabetes Mellitus


Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Enrollment

1,000 participants

Start Date

Jun 6, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

People with type 2 diabetes have a much higher risk of heart disease. One common problem is when the blood vessels that supply the heart become narrowed or blocked by fatty deposits, called plaque. This makes it harder for blood to reach the heart and can lead to serious problems such as chest pain, heart attacks, or even death. This study will follow people with type 2 diabetes who have already had a special heart scan called a coronary CT angiography. This scan takes detailed pictures of the heart's blood vessels. The goal is to understand how heart disease changes over time in people with type 2 diabetes, by looking at repeat scans and other health information. By learning more about how plaque builds up or gets worse, researchers hope to find better ways to identify which patients are most at risk for future heart problems.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how heart artery disease (atherosclerosis — the buildup of fatty plaques in arteries) progresses over time in people with Type 2 diabetes, using repeated CT heart scans to track changes. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with Type 2 diabetes and are currently on medication to control your blood sugar - You have previously had a coronary CT scan (a special heart imaging test) to check for artery disease, and the images were of good quality **You may NOT be eligible if...** - You are unable to provide written consent - You have an unstable medical condition - You have severe kidney disease or known allergy to CT contrast dye - You have Type 1 diabetes Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Amsterdam University Medical Centers

Amsterdam, Netherlands

Cardiology Centers of the Netherlands

Amsterdam, Netherlands

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NCT07237685


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