Coronary Artery Disease (CAD) Clinical Trials

32 recruitingLast updated: June 18, 2026

There are 32 actively recruiting coronary artery disease (cad) clinical trials across 18 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include Beijing, China, Barcelona, Spain, Amsterdam, Netherlands. Updated daily from ClinicalTrials.gov.


Coronary Artery Disease (CAD) Trials at a Glance

32 actively recruiting trials for coronary artery disease (cad) are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Beijing, Barcelona, and Amsterdam. Lead sponsors running coronary artery disease (cad) studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), China National Center for Cardiovascular Diseases, and Fundación EPIC.

Browse coronary artery disease (cad) trials by phase

Treatments under study

About Coronary Artery Disease (CAD) Clinical Trials

Looking for clinical trials for Coronary Artery Disease (CAD)? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Coronary Artery Disease (CAD) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Coronary Artery Disease (CAD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting
Not Applicable

Effects of Myofascial Release on Cardiac Patients After Median Sternotomy

Coronary Artery Disease (CAD)Valve Heart DiseaseAortic Aneurysm and Dissection
Siou-Pin Huang50 enrolled1 locationNCT07649330
Recruiting
Not Applicable

Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)

Heart FailureCoronary Artery DiseaseCoronary Artery Disease (CAD)+5 more
University Medical Center Groningen358 enrolled1 locationNCT07269366
Recruiting

Bern Intracoronary Optical Coherence Tomography and Coronary Computed Tomography Angiography Registry

Coronary Artery Disease (CAD)
Insel Gruppe AG, University Hospital Bern816 enrolled1 locationNCT07565805
Recruiting

AI-assisted CT for Risk Stratification in Coronary Artery Disease (ACTION)

AI (Artificial Intelligence)BiomarkersMyocardial Ischemia+4 more
University of Galway10,000 enrolled1 locationNCT07577609
Recruiting

Coroflex® ISAR NEO PMCF Study

Coronary Artery Disease (CAD)Ischemic Heart Disease
Fundación EPIC3,000 enrolled22 locationsNCT05698732
Recruiting

REGistry of Long-term AnTithrombotic TherApy-1

Peripheral Artery DiseaseCoronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation2,000 enrolled1 locationNCT04347200
Recruiting
Phase 2

A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease

Peripheral Arterial DiseaseCoronary Artery Disease (CAD)
Sirius Therapeutics Co., Ltd.104 enrolled1 locationNCT07318155
Recruiting

Multi-Omics-Based Novel Thrombosis and Bleeding Markers and Risk Model for CHD

ThrombosisBleedingCoronary Artery Disease (CAD)
Xueyan Zhao12,154 enrolled3 locationsNCT07523880
Recruiting
Not Applicable

Fexuprazan for Prevention of Upper Gastrointestinal Bleeding in High Bleeding Risk Patients Receiving Dual Antiplatelet Therapy

Coronary Artery Disease (CAD)acute coronary syndromes (ACS)
SUK MIN SEO400 enrolled1 locationNCT07479056
Recruiting
Not Applicable

Improved Management of Patients With Recent-Onset Stable Chest Pain

Coronary Artery Disease (CAD)
Philipps University Marburg3,369 enrolled39 locationsNCT07476040
Recruiting
Not Applicable

Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease

PreventionCoronary Artery Disease (CAD)Major Adverse Cardiovascular Events (MACE)+1 more
Zhang longjiang,MD3,100 enrolled1 locationNCT06843005
Recruiting

The NAVIGATE-PCI Registry: A New Approach to VIew CT-derived Guidance Ahead of Stenting To Plan Efficient PCI

Coronary Artery Disease (CAD)
HeartFlow, Inc.5,000 enrolled1 locationNCT07479433
Recruiting
Not Applicable

Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

Coronary Artery Disease (CAD)FentanylLeft Ventricular (LV) Systolic Dysfunction+4 more
Cairo University40 enrolled1 locationNCT07248202
Recruiting
Not Applicable

Clinical Outcomes of Drug-Coated Balloons in the Treatment of Patients With Coronary De Novo Chronic Total Occlusion Lesions

Coronary Artery Disease (CAD)Chronic Total Occlusions of Coronary Arterieschronic total occlusion (CTO)
The First Affiliated Hospital of Zhengzhou University200 enrolled18 locationsNCT07463664
Recruiting
Phase 3

Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)

Coronary Artery Disease (CAD)
Sinotau Pharmaceutical Group395 enrolled5 locationsNCT07439133
Recruiting

"Erectile Function After PCI in MI and Non-MI Patients"

AnxietyCoronary Artery Disease (CAD)Diabete Mellitus+2 more
Kırıkkale University100 enrolled1 locationNCT07444697
Recruiting
Not Applicable

Study of Lesion-Specific Invasive Haemodynamic Angina Thresholds

Coronary Artery Disease (CAD)Angina, StableIschaemic Heart Desease
Imperial College London60 enrolled6 locationsNCT07386418
Recruiting

Clinical Implications of Three-vessel Ultrasonic Flow Ratio Measurement in Patients With Coronary Artery Disease

Coronary Artery Disease (CAD)
China National Center for Cardiovascular Diseases494 enrolled1 locationNCT06822894
Recruiting

Assessment and Prediction of Cardiovascular Health and Disease Risk Using Wearable Biometrics.

Cardiovascular Disease PreventionCoronary Artery Disease (CAD)Cardiovascular Diseases (CVD)+1 more
University College Dublin100 enrolled1 locationNCT07401550
Recruiting

Comparison of Upper and Lower Limb Maximal Exercise Capacities and Arterial Stiffness in Patients With CAD

Coronary Artery Disease (CAD)
Gazi University30 enrolled1 locationNCT07148518