RecruitingNCT07242768

Follow-up Extension Study of Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis

Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis: Three-year Follow-up of RESIST Trial


Sponsor

Capital Medical University

Enrollment

1,300 participants

Start Date

Jan 10, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study will include the subjects with symptomatic intracranial arterial stenosis (ICAS) who have participated in and completed the 1-year follow-up of RESIST trial (NCT06615726). The aim is to observe the long-term clinical outcomes over 3 years after a 1-year regular physical exercise intervention in patients with symptomatic ICAS.


Eligibility

Min Age: 40 YearsMax Age: 80 Years

Inclusion Criteria2

  • Participants who enrolled in the RESIST trial and completed the 12-month follow-up.
  • Written informed consent to participate in this 3-year observational extension.

Exclusion Criteria1

  • Participants who withdrew consent in the RESIST trial, decline to participate in this extension, or were lost to follow-up at 12 months.

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Interventions

OTHERNon-Interventional Study

After completing 12-month intervention from RESIST trial, investigators would not make any interventions or impact on subjects.


Locations(1)

Xuanwu Hospital, Capital Medical University

Beijing, China

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NCT07242768


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