RecruitingNot ApplicableNCT07270237

A Study of Multiparametric Ultrasound Imaging Methods

Development and Evaluation of Ultrasound Imaging Acquisition and Analysis Methods

Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

85 participants

Start Date

Nov 24, 2025

Study Type

INTERVENTIONAL

Conditions

Pancreatic Cancer Thyroid Nodule

Summary

The researchers are doing this study to see how well a type of ultrasound imaging called multiparametric ultrasound (mpUS), can be used to examine, evaluate, and provide information about different cancerous and non-cancerous tissue. The researchers will compare the results of mpUS imaging to standard ultrasound imaging and other standard tests. mpUS imaging is a type of ultrasound imaging that combines different ultrasound methods and analysis to create a more detailed and accurate assessment of tissue. Standard ultrasound provides a basic image of tissue structure, but mpUS imaging can also show blood vessels, blood flow, and detailed tissue structure (microstructure). The researchers think that mpUS may be a better way for evaluating cancer because it combines different ultrasound methods to assess tissue.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating new ultrasound imaging techniques to better detect and characterize pancreatic cancer and other conditions like celiac disease and liver steatosis (fatty liver). It uses advanced imaging during standard endoscopic ultrasound procedures — a scope passed down the throat to get images near the pancreas. **You may be eligible if...** - You are already scheduled for an endoscopic ultrasound because you are at high risk for pancreatic cancer (for example, due to family history or a genetic syndrome) - Or you are having a standard endoscopic ultrasound for another reason at a participating hospital - You are 18 or older **You may NOT be eligible if...** - You cannot safely undergo endoscopic ultrasound - You are unable to give consent - You do not meet the specific risk criteria for the relevant study group Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMultiparametric ultrasound (mpUS) imaging

Patients will undergo the added research sequences at any point during their standard of care ultrasound scans, adding up to approximately 15 minutes of added scan time. The only non-routine measurements will be the research ultrasound data.