RecruitingNot ApplicableNCT07270757

Impact of Pre-Ablation Prehabilitation on Clinical Outcomes and Cardiorespiratory Fitness in Atrial Fibrillation Patients

Impact of Pre-Ablation Prehabilitation on Clinical Outcomes and Cardiorespiratory Fitness in Patients With Atrial Fibrillation: A Randomized Controlled Trial


Sponsor

Nanjing Medical University

Enrollment

100 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary objective of this study is to compare the effects of a preoperative prehabilitation program versus usual care on post-procedural cardiorespiratory function and clinical outcomes in patients undergoing catheter ablation for atrial fibrillation.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a supervised exercise program done before a heart ablation procedure (a treatment for irregular heartbeat called atrial fibrillation) can improve fitness and recovery outcomes. Called prehabilitation, this approach aims to get patients in better shape before their procedure. **You may be eligible if...** - You are between 18 and 70 years old - You are scheduled for your first ablation procedure for atrial fibrillation - You have mild to moderate heart failure symptoms (NYHA class I or II) - Your heart's pumping function is 50% or better (preserved ejection fraction) **You may NOT be eligible if...** - You have severe valve disease or other major structural heart problems - You have a condition that prevents safe exercise testing - You have significant cognitive impairment - You have had a prior ablation for atrial fibrillation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHER4-week structured prehabilitation program (exercise training + psychological education)

The prehabilitation group will receive a 4-week structured program before ablation, including: Individualized exercise training: Prescription based on cardiopulmonary exercise test results, including aerobic exercise (40%-60% of heart rate reserve) and resistance training Psychological and educational intervention: Structured education based on cognitive behavioral therapy principles, focusing on addressing kinesiophobia Delivery mode: Hybrid (supervised in-hospital sessions + monitored home-based sessions) The usual care group will receive only standard preoperative education without structured rehabilitation.


Locations(1)

The First Affiliated Hospital with Nanjing Medical University

Nanjing, Please Select, China

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NCT07270757


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