RecruitingNot ApplicableNCT07271043

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

Evaluating the Efficacy of High-Protein Diabetes Specific Formula (HP-DSF) on Body Composition in Overweight/Obese Patients With Type 2 Diabetes Treated With Incretin Mimetic Drugs


Sponsor

Joslin Diabetes Center

Enrollment

60 participants

Start Date

Jan 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized clinical study to assess the efficacy of a high-protein diabetes specific formula (HPDSF) on lean muscle mass in overweight and obese patients with type 2 diabetes who are initiating treatment with incretin-mimetic drugs.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a high-protein medical nutrition formula can help people with type 2 diabetes who are starting a GLP-1 medication (like semaglutide or tirzepatide) preserve their muscle mass while losing weight, since these weight-loss drugs can sometimes cause muscle loss alongside fat loss. **You may be eligible if...** - You are between 18 and 75 years old - You have had type 2 diabetes for at least 3 months - You are about to start a GLP-1 medication (such as Ozempic, Wegovy, Mounjaro, or similar) for the first time - You are otherwise in stable health **You may NOT be eligible if...** - You are already on a GLP-1 medication - You have advanced kidney or liver disease - You have a condition that severely affects digestion or nutrition absorption - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTprotein supplement

HP-DSF shakes (Protality Base or Ensure Max Protein by Abbott Nutrition)


Locations(1)

Joslin Diabetes Center

Boston, Massachusetts, United States

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NCT07271043


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