Periodontal Health and Sodium Bicarbonate Toothpaste
Maintenance of Periodontal Health With Daily Use of Sodium Bicarbonate Toothpaste
University of Plymouth
100 participants
Dec 4, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to determine whether sodium bicarbonate fluoride toothpaste can help maintain periodontal health in adults who have undergone non-surgical periodontal treatment. The main question it aims to answer is: Does daily use of toothpaste affect the following outcomes: clinical oral health (plaque scores, gingival bleeding scores and periodontal pocket depths), salivary biochemical markers and the oral microbiome. Outcomes measures will be recorded at 0,3, and 6 months, during which time participants will receive either the treatment or placebo toothpaste and undergo oral hygiene instruction and PMPR over 6 months.
Eligibility
Inclusion Criteria1
- Adult participants >18 years, of any gender will be recruited.
Exclusion Criteria9
- Full dentures
- Diabetics
- Cancer diagnosis
- Pregnancy
- Use of antibiotics (<3 months prior to participation)
- Use of antibacterial mouthwash
- Inorganic nitrates taken less than 4 weeks before the study
- Immunosuppressants taken less than 4 weeks before the study
- BPE's score of less than 3, and or/ BPE score of more than two 4's.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Baseline; 0 months (no periodontal treatment)
3 months periodontal treatment \& OHI
6 months periodontal treatment \& OHI
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07274189