Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC

This study looks at how a patient's psychological state and immune system response interact during pre-surgery immunotherapy treatment for triple-negative breast cancer (TNBC), which is an aggressive type of breast cancer that lacks the three main hormone receptors. **You may be eligible if...** - You are a woman aged 18 or older - You have been diagnosed with invasive triple-negative breast cancer (confirmed by biopsy) - You are planning to receive immunotherapy-based treatment before surgery as part of your standard care **You may NOT be eligible if...** - Your cancer has spread to other parts of the body (distant metastasis) - You have a history of another cancer (with some exceptions for treated skin cancers) - You have conditions that make immunotherapy unsafe Talk to your doctor to see if this trial is right for you.