Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

This study tests a drug called xaluritamig in children, teenagers, and adults with Ewing sarcoma — a rare cancer that typically affects the bones and surrounding tissue — that has returned or is not responding to treatment. **You may be eligible if...** - You have a confirmed diagnosis of Ewing sarcoma with a specific genetic marker (EWSR1 translocation) - Your cancer has returned or is no longer responding to treatment - You have measurable disease (a tumor that can be tracked on scans) - You are in adequate overall health as determined by the study team **You may NOT be eligible if...** - You do not have the required genetic marker in your tumor - You have certain prior treatments that conflict with the study drug - You have active brain metastases - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.