Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

This study is testing a digital tool called OTX-601 — a smartphone-based program — to see if it can help reduce symptoms of PTSD (post-traumatic stress disorder) by training people to become less sensitive to uncomfortable physical sensations (a technique called interoceptive exposure). **You may be eligible if...** - You have a diagnosis of PTSD - You scored above 24 on the Anxiety Sensitivity Index (ASI-3) - You scored above 30 on the PTSD Checklist (PCL-5) - You understand and speak English - You have a smartphone with internet access **You may NOT be eligible if...** - You scored 24 or below on the ASI-3 or 30 or below on the PCL-5 - You do not have a PTSD diagnosis - You have active psychosis - You were intoxicated during the baseline assessment - You are enrolled in another treatment research study - You have a medical condition that prevents you from doing physical breathing or body awareness exercises Talk to your doctor to see if this trial is right for you.