RecruitingNot ApplicableNCT07334392

Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment

Effectiveness of an Innovative Therapeutic Exercise Program on Physical and Cognitive Function in Mild Cognitive Impairment Due to Alzheimer's Disease


Sponsor

University of Patras

Enrollment

45 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment. The main questions it aims to answer are: Does the innovative therapeutic exercise program improve gait and balance? Does the innovative therapeutic exercise program improve cognition? Researchers will compare the innovative therapeutic exercise program emphasizing in dual-task exercises to a therapeutic exercise program without emphasizing in dual-task exercises and to a control group (given instruction about the benefits of exercise). Participants will: * Perform the exercise program twice a week for three months. * Will be assessed before and after the intervention. * Will record The Borg Scale of Perceived Exertion every second week to monitor and assess the progression of exercise intensity.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a combined exercise program (including strength, balance, and aerobic training) can improve memory, thinking ability, and physical function in older adults with mild cognitive impairment — early-stage memory and thinking difficulties that aren't yet dementia. **You may be eligible if...** - You are over 50 years old - You have been diagnosed with mild cognitive impairment (confirmed by a cognitive test scoring above 20 on the MoCA) - Your medications have been stable for at least the past month - You can walk independently **You may NOT be eligible if...** - You have been diagnosed with dementia - You have a chronic mental illness (e.g., schizophrenia or bipolar disorder) - You have a neurological disorder (e.g., Parkinson's, multiple sclerosis, or brain injury) - You have clinical depression - You have had recent surgery - You do not have sufficient knowledge of Greek (this study is conducted in Greece) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERInnovative therapeutic exercise program

Aerobic, strengthening and balance exercises combined with cognitive training -name: Experimental group 1 (EXP1)

OTHERTherapeutic exercise program

Aerobic, strengthening and balance exercises without cognitive training- name: Experimental group 2 (EXP2)

OTHERFlyer

The control group will receive only educational material in the form of a flyer, outlining the importance and potential benefits of physical activity, along with general lifestyle recommendations, without participating in the structured exercise intervention- name: Control group (CG)


Locations(1)

Department of Physiotherapy, University of Patras

Pátrai, Greece

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NCT07334392


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