RecruitingNot ApplicableNCT07335263

Effects of Swaddling and Nesting on Pain and Stress in Newborns

The Effect of Swaddling and Nesting Methods on Pain and Stress Levels in Newborns Undergoing Noninvasive Mechanical Ventilation


Sponsor

Kutahya Health Sciences University

Enrollment

100 participants

Start Date

Feb 17, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the effects of swaddling and cradling methods on pain and stress levels in newborn infants receiving respiratory support. Infants receiving respiratory support in the neonatal intensive care unit may experience stress and discomfort during treatment. In this study, two different care methods that help infants feel more comfortable and secure will be scientifically compared. Only one of the Swaddling or Nesting methods will be applied to the newborns participating in the study. These methods are comfort-enhancing care practices routinely used in neonatal intensive care that do not harm the baby. The newborn's heart rate, respiratory rate, oxygen level, pain and stress symptoms will be closely and safely monitored by the healthcare team. A pain-free saliva sample will be collected to assess the newborn's stress level. It does not involve needles, does not hurt, and takes approximately 2 minutes. Pain and stress levels will be assessed in a multifaceted manner using clinical observation, physiological parameters, and saliva cortisol levels. The study aims to contribute to the strengthening of evidence-based non-pharmacological care practices in neonatal intensive care.


Eligibility

Min Age: 0 DaysMax Age: 28 Days

Inclusion Criteria4

  • Birth week greater than 35 weeks and birth weight greater than 2000 grams
  • Requirement for nasal CPAP/noninvasive mechanical ventilation
  • Legal guardians' consent to participate in the study
  • Postnatal diagnosis of transient tachypnea of the newborn

Exclusion Criteria18

  • Mother:
  • Taking cortisol-containing medication during the antenatal period
  • Taking narcotics during the antenatal period
  • Having chorioamnionitis
  • Having a metabolic disorder (adrenal insufficiency, etc.)
  • Newborn:
  • Amniotic fluid stained with meconium
  • Being intubated
  • Having an Apgar score below 6
  • Receiving analgesic or narcotic drugs for sedation
  • The newborn receiving cortisol-containing medication
  • Being unable to obtain a saliva sample or the sample being contaminated with blood
  • Signs of nasal injury during noninvasive mechanical ventilation
  • Congenital defects (spina bifida, gastroschisis, etc.) that prevent positioning using the swaddling or cradling methods
  • Resuscitation
  • Cerebral hypoxia-ischemia
  • Non-respiratory causes (congenital pneumonia, respiratory distress syndrome, congenital heart disease, hypocalcemia, persistent hypoglycemia, development of sepsis)
  • Hypocalcemia (low calcium level detected in blood gas sample taken while establishing an intravenous line prior to nCPAP)

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Interventions

BEHAVIORALswaddling

Saliva samples will be collected before the swaddling method is applied (t1), during application (5th minute) (t2), and 30 minutes after the swaddling method is applied (t3). Heart rate, respiratory rate, and partial oxygen pressure values, as well as pain and stress levels (ALPS-Neo), will be recorded by two researchers.

BEHAVIORALNesting

Saliva samples will be collected before the nesting method is applied (t1), during application (5th minute) (t2), and 30 minutes after the nesting method is applied (t3). Heart rate, respiratory rate, and partial oxygen pressure values, as well as pain and stress levels (ALPS-Neo), will be recorded by two researchers.


Locations(1)

Kütahya Health Sciences University

Merkez, Kütahya, Turkey (Türkiye)

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NCT07335263


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