Stress and Pain in People Living With HIV

This study is examining how stress and cannabis use affect pain in people living with HIV. Researchers want to understand whether people with HIV who also use cannabis and have depression experience pain differently, and whether stress plays a role. **You may be eligible if...** - You are HIV-positive with an undetectable viral load and good adherence to HIV treatment - You are in good general health based on a screening exam - You can read English and complete study questionnaires - If you are in the cannabis user group: you have a positive urine test for cannabis and meet criteria for cannabis use disorder and depression - If you are a healthy comparison participant: you are HIV-negative with no major medical or psychiatric conditions **You may NOT be eligible if...** - Your HIV is not well-controlled - You have significant untreated medical or psychiatric conditions - You are unable to complete the study evaluations Talk to your doctor to see if this trial is right for you.