Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia
Evaluation of sFlt-1/PlGF Ratio, Osteoprotegerin (OPG) and Soluble Endoglin (sEng) as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia
Ammar Jassim Abed
120 participants
Oct 10, 2025
OBSERVATIONAL
Conditions
Summary
his study investigates the effectiveness of three specific biological markers (biomarkers) in the blood-the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)-to better diagnose and monitor preeclampsia. Preeclampsia is a serious pregnancy complication characterized by high blood pressure and potential organ damage that affects 2-8% of pregnancies worldwide
Eligibility
Inclusion Criteria3
- Pregnant women between 20 and 36 weeks of gestation
- Age between 18 and 45 years
- Attending the antenatal clinic at the study site
Exclusion Criteria5
- Chronic hypertension
- Renal disease
- Diabetes mellitus
- Multiple gestations
- Autoimmune disorders
Locations(1)
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NCT07349277