RecruitingNCT07349277

Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia

Evaluation of sFlt-1/PlGF Ratio, Osteoprotegerin (OPG) and Soluble Endoglin (sEng) as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia


Sponsor

Ammar Jassim Abed

Enrollment

120 participants

Start Date

Oct 10, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

his study investigates the effectiveness of three specific biological markers (biomarkers) in the blood-the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)-to better diagnose and monitor preeclampsia. Preeclampsia is a serious pregnancy complication characterized by high blood pressure and potential organ damage that affects 2-8% of pregnancies worldwide


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Inclusion Criteria3

  • Pregnant women between 20 and 36 weeks of gestation
  • Age between 18 and 45 years
  • Attending the antenatal clinic at the study site

Exclusion Criteria5

  • Chronic hypertension
  • Renal disease
  • Diabetes mellitus
  • Multiple gestations
  • Autoimmune disorders

Locations(1)

Bint Al Huda Maternity Hospital

Nasiriyah, Dhi Qar, Iraq

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NCT07349277


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