RecruitingNCT07349277

Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia

Evaluation of sFlt-1/PlGF Ratio, Osteoprotegerin (OPG) and Soluble Endoglin (sEng) as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia


Sponsor

Ammar Jassim Abed

Enrollment

120 participants

Start Date

Oct 10, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

his study investigates the effectiveness of three specific biological markers (biomarkers) in the blood-the sFlt-1/PlGF ratio, soluble endoglin (sEng), and osteoprotegerin (OPG)-to better diagnose and monitor preeclampsia. Preeclampsia is a serious pregnancy complication characterized by high blood pressure and potential organ damage that affects 2-8% of pregnancies worldwide


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating whether three blood markers — sFlt-1/PlGF ratio, OPG, and sEng — can predict and help diagnose preeclampsia, a serious blood pressure complication of pregnancy. Finding reliable blood tests to detect preeclampsia early could help doctors intervene sooner and protect both mother and baby. **You may be eligible if...** - You are pregnant, between 20 and 36 weeks of pregnancy - You are between 18 and 45 years old - You are attending antenatal (prenatal) care at the study site **You may NOT be eligible if...** - You had high blood pressure before pregnancy - You have kidney disease - You have diabetes - You are carrying more than one baby (multiple gestation) - You have an autoimmune disorder Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Bint Al Huda Maternity Hospital

Nasiriyah, Dhi Qar, Iraq

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NCT07349277


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