RecruitingNot ApplicableNCT07378839

Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting


Sponsor

University of Minnesota

Enrollment

100 participants

Start Date

Feb 10, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during their first trimester.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria4

  • Pregnant individuals aged 18 years or older
  • Viable pregnancy with a gestational age between 6 0/7 - 12 6/7 weeks of gestation, confirmed by last menstrual period or ultrasound
  • Diagnosed with mild to moderate NVP (PUQE-24 score between 4-12)
  • Ability to understand and read English

Exclusion Criteria5

  • Severe nausea and vomiting, defined as a PUQE score \>12, or diagnosis of hyperemesis gravidarum requiring hospitalization or intravenous fluid therapy
  • Pre-existing, active or acute respiratory conditions (e.g., asthma, COPD)
  • History of severe anxiety disorders affecting breathing patterns
  • Known deviated nasal septum
  • Nausea and vomiting that pre-dates the pregnancy or is suspected to be due to a etiology other than pregnancy

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Interventions

BEHAVIORALAlternate Nostril Breathing

ANB 3 times per day for 5-10 minutes per session over a 7-day period


Locations(1)

University of Minnesota

Minneapolis, Minnesota, United States

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NCT07378839


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