Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

This study is using artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease and related conditions. The goal is to identify digital biomarkers — measurable patterns — that can help doctors detect and monitor Parkinson's more objectively and non-invasively. **You may be eligible if...** - You are 18 to 75 years old - You have been diagnosed with Parkinson's disease (PD), multiple system atrophy (MSA), or progressive supranuclear palsy (PSP) by a movement disorder specialist - You are willing to have video and audio recordings taken of your facial expressions and speech - You are able to give informed consent **You may NOT be eligible if...** - You do not meet the diagnostic criteria for the conditions being studied - You are unwilling to be recorded - You have severe cognitive impairment that prevents informed consent - You have another condition that significantly affects facial expression or speech unrelated to Parkinson's Talk to your doctor to see if this trial is right for you.