Music-Augmented Rhythmic Gait Training in Multiple Sclerosis
Music-Augmented Versus Non-Music Technology-Based Rhythmic Gait Training in Multiple Sclerosis: A Randomized Controlled Trial of Gait Performance and Clinical Outcomes
Biruni University
32 participants
Jan 20, 2026
INTERVENTIONAL
Conditions
Summary
This randomized controlled trial aims to compare the effects of technology-based rhythmic gait training performed with and without music on walking performance and clinical outcomes in individuals with multiple sclerosis (MS). Thirty-two participants with mild to moderate disability will be randomly assigned to either a music-assisted rhythmic gait training group or a non-music control group, with both interventions delivered via telerehabilitation. Outcomes related to gait performance, balance, fatigue, and cognitive function will be assessed before and after a four-week intervention period.
Eligibility
Inclusion Criteria4
- Expanded Disability Status Scale (EDSS) score between 0 and 4.0
- Access to the internet via a high-speed smartphone or computer
- A score of at least 21 on the Montreal Cognitive Assessment (MoCA)
- Functional Ambulation Scale score of Stage 3 or higher
Exclusion Criteria6
- Presence of hearing or visual impairments
- Current participation in any structured exercise program
- Presence of other neurological, cardiovascular, or orthopedic disorders
- History of MS relapse or change in disease-modifying treatment within the last 6 months
- Physical conditions preventing safe participation in the exercise program
- Comorbid conditions that adversely affect oxygen transport (e.g., severe anemia, peripheral arterial disease)
Interventions
rticipants will perform standardized breathing exercises and general mobility exercises. These exercises will be delivered in the same telerehabilitation format and supervised by a physiotherapist.
Participants will perform rhythmic gait training accompanied by music. The training will be delivered via telerehabilitation with real-time supervision through videoconferencing. Sessions will be conducted four days per week for four weeks. Gait training will be guided using instructional videos presented with music accompaniment.
Participants will perform the same rhythmic gait training program without music. The training will be delivered via telerehabilitation with real-time supervision through videoconferencing. Sessions will be conducted four days per week for four weeks. Gait training will be guided using instructional videos presented without music (silent).
Locations(1)
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NCT07399262