RecruitingNot ApplicableNCT07406295

Respiratory Muscle Training to Improve Cerebrovascular and Immune Function

Novel Respiratory Muscle Training for Improving Cerebrovascular Function and Immune Status in Adults With Obesity


Sponsor

Florida State University

Enrollment

30 participants

Start Date

Jan 27, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals feel they do not have time to exercise. There is a need for a quicker type of training that improves brain health. Newly developed breathing exercises could be a time-efficient, cost-effective, and home-based practice to increase brain health. This practice acts as weightlifting for breathing muscles. These new breathing exercises have already been shown to increase heart health. Heart health is linked to brain health; if an intervention helps the heart, it is likely to also help the brain. It is currently unknown if breathing training can improve brain health in younger adults with obesity. The investigators will utilize the same 8-week program shown to improve heart health. Testing will be conducted before and after the breathing training. The first part of the study will determine if breathing exercises help brain health. Obesity also causes inflammation. This is measured via blood but affects the entire body. It is thought to cause some of the negative outcomes of obesity. By lowering inflammation, it is likely to improve overall health. Breathing exercises may reduce inflammation, but more research is required. The second part of this study will determine whether breathing exercises help reduce inflammation. This study will determine if brain health can be improved in adults with obesity. This could help 40% of American adults with obesity to live longer and healthier lives.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called High intensity inspiratory muscle strength training and a medical device called Low intensity for people with cerebrovascular function, immune cells activity, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEHigh intensity inspiratory muscle strength training

This intervention will aim to increase inspiratory strength in adults with obesity to improve cerebrovascular function and immune status.

DEVICELow intensity

Very-low-resistance inspiratory muscle strength training


Locations(1)

Florida State University

Tallahassee, Florida, United States

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NCT07406295


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