Non-invasive Brain Stimulation in Multiple Sclerosis Fatigue

This study is testing non-invasive brain stimulation techniques to help reduce fatigue in people with relapsing-remitting multiple sclerosis (MS) — the most common type of MS where symptoms come and go. The study includes both MS patients who experience fatigue and those who do not, to compare effects. **You may be eligible if...** - You are between 18 and 70 years old - You have a confirmed diagnosis of relapsing-remitting MS - Your MS disability level is mild (EDSS score of 4 or below) - You have had MS for 10 years or less - Your MS treatment has been stable (or you are not on treatment) for the last 6 months - You have health insurance **You may NOT be eligible if...** - You cannot have an MRI (e.g., due to metal implants) - You have another significant neurological, immune, or psychiatric condition besides MS (depression is sometimes acceptable) - You are taking certain medications that affect brain chemistry (such as levodopa, fluoxetine, paroxetine, or antipsychotics) - You had an MS relapse or took steroids in the last 4 weeks - You have a sleep disorder - You are on certain MS disease-modifying therapies (other than B-cell depleting drugs or fumarates) Talk to your doctor to see if this trial is right for you.